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Zoological Studies

Table 1 Identification of the 37 amino acids of IAPP using PCR and sequencing

From: Anatomic and molecular characterization of the endocrine pancreas of a teleostean fish: Atlantic wolffish (Anarhichas lupus)

                                      

Agg

                                      

Segment

 

1

        

10

         

20

         

30

       

19-34

Human

K

C

N

T

A

T

C

A

T

Q

R

L

A

N

F

L

V

H

S

S

N

N

F

G

A

I

L

S

S

T

N

V

G

S

N

T

Y

23

Cat

K

C

N

T

A

T

C

A

T

Q

R

L

A

N

F

L

I

R

S

S

N

N

L

G

A

I

L

S

P

T

N

V

G

S

N

T

Y

9

Rat

K

C

N

T

A

T

C

A

T

Q

R

L

A

N

F

L

V

R

S

S

N

N

L

G

P

I

L

P

P

T

N

V

G

S

N

T

Y

0

Atlantic wolffish

                  

S

S

P

S

R

S

G

I

S

P

R

N

T

Y

G

K

   

0

Atlantic salmon

        

T

Q

R

L

A

D

F

L

T

R

S

S

N

T

I

G

T

V

Y

A

P

T

N

V

G

S

   

17

Daddy sculpin

                  

S

N

S

T

I

G

T

V

N

A

P

T

N

V

G

S

   

2

Zebrafish

                

T

R

S

S

S

P

I

G

T

V

N

A

P

T

N

V

G

S

   

0

  1. The amino acid sequences of teleost fish are compared to the amyloidogenic (human, cat) or non-amyloidogenic (rat) sequences. Sequences from species written in italics were obtained from a published work (Westermark et al. 2002). The Agg parameters were obtained using the Tango algorithm. The amino acids in boldface represent amino acid variations between species.
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