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Table 1 Identification of the 37 amino acids of IAPP using PCR and sequencing

From: Anatomic and molecular characterization of the endocrine pancreas of a teleostean fish: Atlantic wolffish (Anarhichas lupus)

                                       Agg
                                       Segment
  1          10           20           30         19-34
Human K C N T A T C A T Q R L A N F L V H S S N N F G A I L S S T N V G S N T Y 23
Cat K C N T A T C A T Q R L A N F L I R S S N N L G A I L S P T N V G S N T Y 9
Rat K C N T A T C A T Q R L A N F L V R S S N N L G P I L P P T N V G S N T Y 0
Atlantic wolffish                    S S P S R S G I S P R N T Y G K     0
Atlantic salmon          T Q R L A D F L T R S S N T I G T V Y A P T N V G S     17
Daddy sculpin                    S N S T I G T V N A P T N V G S     2
Zebrafish                  T R S S S P I G T V N A P T N V G S     0
  1. The amino acid sequences of teleost fish are compared to the amyloidogenic (human, cat) or non-amyloidogenic (rat) sequences. Sequences from species written in italics were obtained from a published work (Westermark et al. 2002). The Agg parameters were obtained using the Tango algorithm. The amino acids in boldface represent amino acid variations between species.