Table 4 Proteins from cellular vacuoles, ribonucleoprotein particles (vaults), nuclei and mitochondria
From: Proteomic study of the brackish water mussel Mytilopsis leucophaeata
Protein | Eucaryote | Function | Localisation |
|---|---|---|---|
V-type proton ATPase catalytic subunit A [P314400] | Manduca sexta (tobacco horn worm) | Involved in cellular trafficking, exocytosis and endocytosis, and interaction with the cytoskeleton (Marshansky and Futai 2008) | Cellular vacuoles |
Major vault protein [Q5EAJ7] | Strongylocentrotus purpuratus (purple sea urchin) | Signal pathway regulation and immune defence (Berger et al. 2009) | Ribonucleoprotein particles (41 × 41 × 71.5 nm) or vaults |
Histone H2A.V [P02272] | Gallus gallus (chicken) | Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability | Part of nucleosome core (nuclei) |
Histone H2A [P02268] | Sepia officinalis (common cuttlefish) | See above and below | See above and below |
Histone H2B, gonadal [P02284] | Patella granatina (sand paper limpet) | See above; further, histones and histone fragments circulate via transporters through the cytoplasm and so may be transferred to the plasma membrane (Schuurmans Stekhoven et al. 2004) from where they execute their anti-microbial activity (Seo et al. 2011) | Nuclei, cytoplasm, and plasmalemma |
Histone H3 [P02299] | Drosophila melanogaster (fruit fly) | See above | See over |
Histone H4 [P35059] | Acropora formosa (stony corals) | See above | See over |
Proteasome subunit α type-2 [Q73672] | Carassius auratus (gold fish) | Cleavage of peptide bonds with very broad specificity | Cytoplasm and nucleus |
Proteasome subunit α type-5-A [O81149] | Arabidopsis thaliana (thale cress) | Brake down of damaged or redundant proteins | Cytosol and nucleus |
Proteasome subunit α type-7 [O13268] | Gallus gallus (chicken) | ATP dependent cleavage of peptide bonds with broad specificity | Cytoplasm and nucleus |
14-3-3 protein ε [P92177] | Drosophila melanogaster (fruit fly) | Multifunctional: regulation of enzymatic activity, regulation of subcellular localisation, inhibition of protein-protein or protein-DNA interaction, protection against dephosphorylation or proteolytic degradation, stabilisation of multiprotein complexes (Obsil and Obsilova 2011) | Plasmalemma, mitochondrion, nucleus |
ATP synthase, subunit α [Q9XXK1] | Caenorhabditis elegans (round worm) | ATP synthesis | Mitochondrion |
ATP synthase, subunit β precursor [Q5ZLC5] | Gallus gallus (chicken) | ATP synthesis | Mitochondrion |
Succinate dehydrogenase [Q28ED0] | Xenopus tropicalis (Western clawed frog) | Transfer of electrons to coenzyme Q | Mitochondrion |
ADP/ATP carrier protein 3 [O49447] | Arabidopsis thaliana (thale cress) | Exchange of ADP and ATP across the mitochondrial inner membrane | Idem |
Probable malate dehydrogenase 3 [Q54VM2] | Dictyostelium discoideum (amoeba) | Oxidation of malate to oxaloacetate | Cytoplasm and mitochondria (Danis and Farkas 2009; Gietl 1992) |
Phosphoenolpyruvate carboxykinase [Q05893] | Ascaris suum (pig roundworm) | Conversion of oxaloacetate to phosphoenolpyruvate and vice versa | Mitochondria (Stryer 1995b) |