From: Proteomic study of the brackish water mussel Mytilopsis leucophaeata
Protein | Eucaryote | Function | Localisation |
---|---|---|---|
Cytoplasmic actin [Q93129] | Branchiostoma Belcheri (Belcher's lancelet) | Transport track for myosin + support of cell stability (Pollard and Cooper 2009) | Cytoskeleton |
Actin, cytoplasmic 1 (β-actin) [P79818] | Oryzias latipes (Japanese medaka) | Idem | Idem |
Actin [O16808] | Maietiola destructor (Hessian fly or barley midge) | Cell support + providing trafficking routes for myosin in signal transduction (Pollard and Cooper) | cytoskeleton, microfilaments |
Actin, cytoskeletal 1A [P53472] | Strongylocentrotus purpuratus (purple sea urchin) | Idem | Idem |
Actin, non-muscle 6.2 [P17126] | Hydra vulgaris (fresh water polyp) | Idem | Idem |
Actin-3 [P53457] | Diphyllobothrium dentricum (flatworm) | Idem in metazoan muscle cells actin forms a scaffold in which myosin generates force to support muscle contraction | Idem |
Actin-3 [P41113] | Podocoryne carnea (jellyfish) | As for cytoplasmic actin | Idem |
Actin-18 [P07828] | Dictyostelium discoideum (amoeba) | Idem | Idem |
Actin [O17320] | Crassostrea gigas (Pacific oyster) | Idem | Idem |
Actin [P50138] | Puccinia graminis(mould) | Idem | Idem |
Actin, clone 205 [P18600] | Artemia sp. (crustacean) | Idem | Idem |
Plastin-1 [P19179] | Gallus gallus (chicken) | Actin bundling protein | Cytoskeleton |
Spectrin α-chain, non-erythrocytic 1 [P07751] | Gallus gallus | Playing an important role in membrane organisation | Cytoplasm, cytoskeleton and cell cortex |
Spectrin β-chain [Q00963] | Drosophila melanogaster (fruit fly) | Spectrin links the actin cytoskeleton to the plasma membrane, thus forming a flexible scaffold in the cell cortex (Djinovic-Carugo et al. 2002) | Plasmalemma + cytoskeleton |
Heat shock cognate protein HSP90-β [Q04619] | Gallus gallus (chicken) | Early embryonic development, germ cell maturation, cytoskeletal stabilisation, cellular transformation, signal transduction, long-term cell adaptation (Sreedhar et al. 2004) | Cytoplasm + cytoskeleton (microtubules and actin filaments, Cambiazo et al. 1999) |
Radixin [P26043] | Mus musculus (mouse) | Participates in signal transduction and regulates cell migration and intercellular adhesion via Rac 1 (Valderrama et al. 2012) | Linking plasmalemma to actin filaments |
Ubiquitin [Q86WD4] | Encephalitozoon cuniculi (protozoan) | Involved in the ubiquitin proteasome pathway (Hegde 2010) | Plasmalemma and cytoskeleton (microtubules) (Murti et al. 1988, Hicke and Dunn 2003) |
T-complex protein 1 subunit α [P50157] | Ambystoma mexicanum (axolotl, salamander) | TCP-1 is chaperonin, involved in protein folding, e.g. of actin and tubulin (Souès et al. 2003; Yam et al. 2008) | Nucleus, cytoskeleton (microtubule organising centre) and cytoplasm (Souès et al. 2003) |
Tubulin β-chain [P11833] | Paracentrotus lividus (sea urchin) | Mitosis, intracellular vesicle transport (www.buzzle.com/articles/microtubules-function. html) | Part of cytoskeleton: microtubules |
Tubulin β-2 chain [P52275] | Caenorhabditis elegans | Part of transport track for ATP-driven vesicle movement or chromosomes in mitosis and meiosis | Cytoskeleton: microtubules |
Tubulin α-1A chain [A5A6J1] | Pan troglodytes (chimpanzee) | Involved in supporting the cell shape and transport of vesicles | Idem |
Tubulin α-3 chain [P05214] | Mus musculus (house mouse) | cf. Tubulin β-chains | Idem |
Myosin-9 [P35579] | Homo sapiens (human) | Cytokinesis: vesicle transport via actin filaments, cell shape, secretion and capping | Cytoskeleton, cell cortex together with actin filaments at lamellipodia and at the leading edge of migrating cells |
Elongation factor 1α [P02993] | Artemia salina (brine shrimp) | Promoting the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis | Cytoskeleton (actin filaments) (Liu et al. 1996) |
Eucaryotic initiation factor 4A-I [A5A6N4] | Pan troglodytes (chimpanzee) | ATP-dependent RNA helicase, involved in mRNA binding to the ribosome | Cytoskeleton (Ziegler et al. 2012) |
Myosin-11 [P10587] | Gallus gallus (chicken) | Involved in contraction | Smooth muscle |
Myosin catalytic light chain LC-1 [P05945] | Todarus pacificus (Japanese flying squid = cephalopod) | Is dependent on Ca2+ binding for muscle contraction; in molluscan muscle Ca2+ regulation is associated with myosin rather than with actin | Mantle muscle |
Myosin essential adductor muscle light chain [P07290] | Mizuhopecten yessoensis (Yesso scallop, bivalve) | Idem | Idem |
Paramyosin [O96064] | Mytilus galloprovincialis (Mediterranean mussel) | Attachment to the substrate | Mytilus anterior byssus retractor paramyosin (thick filaments at the myofibrils) |
Adductor muscle actin (precursor) [Q26065] | Placopecten magellanicus (sea scallop) | Involved in muscle contraction | Location is in the name |
Actin, muscle (precursor) [P12431] | Strongylocentrotus purpuratus (purple sea urchin) | Is involved in muscle contraction | Idem |
Tropomyosin [Q9GZ71] | Haliotis diversicolor (variously coloured abalone) | In association with the troponin complex plays a central role in the Ca2+-dependent regulation of muscle contraction | Idem |
α-Actinin, sarcomeric [P18091] | Drosophila melanogaster (fruit fly) | F-actin cross-linking protein, anchoring actin to a variety of intracellular structures. By allowing insertion of thick filaments (myosin) the thin filaments (actin) are led to contraction (Stryer 1995a) |  |
Actin, larval muscle [P02574] | Drosophila melanogaster (fruit fly) | Actin, together with myosin, is involved in muscle contraction | Â |
Myosin heavy chain, striated muscle [P24733] | Argopecten irradians (baby scallop) | Involved in muscle contraction (Nyitray et al. 1991) | Â |