Skip to main content

Advertisement

Table 3 Proteins of cytoskeleton and muscle

From: Proteomic study of the brackish water mussel Mytilopsis leucophaeata

Protein Eucaryote Function Localisation
Cytoplasmic actin [Q93129] Branchiostoma Belcheri (Belcher's lancelet) Transport track for myosin + support of cell stability (Pollard and Cooper 2009) Cytoskeleton
Actin, cytoplasmic 1 (β-actin) [P79818] Oryzias latipes (Japanese medaka) Idem Idem
Actin [O16808] Maietiola destructor (Hessian fly or barley midge) Cell support + providing trafficking routes for myosin in signal transduction (Pollard and Cooper) cytoskeleton, microfilaments
Actin, cytoskeletal 1A [P53472] Strongylocentrotus purpuratus (purple sea urchin) Idem Idem
Actin, non-muscle 6.2 [P17126] Hydra vulgaris (fresh water polyp) Idem Idem
Actin-3 [P53457] Diphyllobothrium dentricum (flatworm) Idem in metazoan muscle cells actin forms a scaffold in which myosin generates force to support muscle contraction Idem
Actin-3 [P41113] Podocoryne carnea (jellyfish) As for cytoplasmic actin Idem
Actin-18 [P07828] Dictyostelium discoideum (amoeba) Idem Idem
Actin [O17320] Crassostrea gigas (Pacific oyster) Idem Idem
Actin [P50138] Puccinia graminis(mould) Idem Idem
Actin, clone 205 [P18600] Artemia sp. (crustacean) Idem Idem
Plastin-1 [P19179] Gallus gallus (chicken) Actin bundling protein Cytoskeleton
Spectrin α-chain, non-erythrocytic 1 [P07751] Gallus gallus Playing an important role in membrane organisation Cytoplasm, cytoskeleton and cell cortex
Spectrin β-chain [Q00963] Drosophila melanogaster (fruit fly) Spectrin links the actin cytoskeleton to the plasma membrane, thus forming a flexible scaffold in the cell cortex (Djinovic-Carugo et al. 2002) Plasmalemma + cytoskeleton
Heat shock cognate protein HSP90-β [Q04619] Gallus gallus (chicken) Early embryonic development, germ cell maturation, cytoskeletal stabilisation, cellular transformation, signal transduction, long-term cell adaptation (Sreedhar et al. 2004) Cytoplasm + cytoskeleton (microtubules and actin filaments, Cambiazo et al. 1999)
Radixin [P26043] Mus musculus (mouse) Participates in signal transduction and regulates cell migration and intercellular adhesion via Rac 1 (Valderrama et al. 2012) Linking plasmalemma to actin filaments
Ubiquitin [Q86WD4] Encephalitozoon cuniculi (protozoan) Involved in the ubiquitin proteasome pathway (Hegde 2010) Plasmalemma and cytoskeleton (microtubules) (Murti et al. 1988, Hicke and Dunn 2003)
T-complex protein 1 subunit α [P50157] Ambystoma mexicanum (axolotl, salamander) TCP-1 is chaperonin, involved in protein folding, e.g. of actin and tubulin (Souès et al. 2003; Yam et al. 2008) Nucleus, cytoskeleton (microtubule organising centre) and cytoplasm (Souès et al. 2003)
Tubulin β-chain [P11833] Paracentrotus lividus (sea urchin) Mitosis, intracellular vesicle transport (www.buzzle.com/articles/microtubules-function. html) Part of cytoskeleton: microtubules
Tubulin β-2 chain [P52275] Caenorhabditis elegans Part of transport track for ATP-driven vesicle movement or chromosomes in mitosis and meiosis Cytoskeleton: microtubules
Tubulin α-1A chain [A5A6J1] Pan troglodytes (chimpanzee) Involved in supporting the cell shape and transport of vesicles Idem
Tubulin α-3 chain [P05214] Mus musculus (house mouse) cf. Tubulin β-chains Idem
Myosin-9 [P35579] Homo sapiens (human) Cytokinesis: vesicle transport via actin filaments, cell shape, secretion and capping Cytoskeleton, cell cortex together with actin filaments at lamellipodia and at the leading edge of migrating cells
Elongation factor 1α [P02993] Artemia salina (brine shrimp) Promoting the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis Cytoskeleton (actin filaments) (Liu et al. 1996)
Eucaryotic initiation factor 4A-I [A5A6N4] Pan troglodytes (chimpanzee) ATP-dependent RNA helicase, involved in mRNA binding to the ribosome Cytoskeleton (Ziegler et al. 2012)
Myosin-11 [P10587] Gallus gallus (chicken) Involved in contraction Smooth muscle
Myosin catalytic light chain LC-1 [P05945] Todarus pacificus (Japanese flying squid = cephalopod) Is dependent on Ca2+ binding for muscle contraction; in molluscan muscle Ca2+ regulation is associated with myosin rather than with actin Mantle muscle
Myosin essential adductor muscle light chain [P07290] Mizuhopecten yessoensis (Yesso scallop, bivalve) Idem Idem
Paramyosin [O96064] Mytilus galloprovincialis (Mediterranean mussel) Attachment to the substrate Mytilus anterior byssus retractor paramyosin (thick filaments at the myofibrils)
Adductor muscle actin (precursor) [Q26065] Placopecten magellanicus (sea scallop) Involved in muscle contraction Location is in the name
Actin, muscle (precursor) [P12431] Strongylocentrotus purpuratus (purple sea urchin) Is involved in muscle contraction Idem
Tropomyosin [Q9GZ71] Haliotis diversicolor (variously coloured abalone) In association with the troponin complex plays a central role in the Ca2+-dependent regulation of muscle contraction Idem
α-Actinin, sarcomeric [P18091] Drosophila melanogaster (fruit fly) F-actin cross-linking protein, anchoring actin to a variety of intracellular structures. By allowing insertion of thick filaments (myosin) the thin filaments (actin) are led to contraction (Stryer 1995a)  
Actin, larval muscle [P02574] Drosophila melanogaster (fruit fly) Actin, together with myosin, is involved in muscle contraction  
Myosin heavy chain, striated muscle [P24733] Argopecten irradians (baby scallop) Involved in muscle contraction (Nyitray et al. 1991)